Sometimes when I'm bored I like to go to domain registration sites and check out what .com's are still available. It's fairly amazing what hasn't been taken yet, as evidenced by the sites below. And I'm not just guessing either, I've checked and they are all currently available.
ThisWeekInSlamPoetry.com - how many flavors of newsletter can you write?
ProveItToJohnWayne.com - you can't dupe the Duke
GreasedMormon.com - send in those pictures!
RetiredSuperheroes.com - what's Plastic Man up to these days?
Paramount-Studios.com - be a mogul!
ArmwrestleMe.com - challenge visitors to online matches
KnittingWithHate.com - a sassy hood and robe are a snap!
KingOfAllCreation.com - i'm actually just shocked this isn't taken
BestCookInTexas.com - are you the best cook in Texas? you are now!
EraseYourDebtIllegally.com - best for offshore webmasters
LookingForCurtains.com - who doesn't look for curtains? this is a goldmine waiting for someone to claim it.
SearingGasPain.com - share stories about your experiences with intense, searing gas pain
BuyMeSomeSocks.com - need socks? say it's web 2.0 and they'll come rolling in!
WayToBeUgly.com - sarcastically captioned photos of the unfortunate-looking
PopsicleHolocaust.com - a band? a movie? let your imagination run wild!
SonyTimeWarner.com - get it now before it happens!
ExtraLargeFries.com - is it a site about orders involving large quantities of fries, or individual fries which are abnormally large? you decide!
And I'm sure there are many more. I mean, I guess there are. Unless I just got really lucky with my choices. So you have no excuse for not getting somewhat close to the domain name of your dreams. Even if you want to call your site WebsiteOfYourDreams.com, because that's available too.